The biology of it all

Bruce Marshall describes the journey of developing biologic knowledge of Cystic Fibrosis (CF), an inherited condition. He illustrates the variety of methods that contributed to this development and suggests how CF knowledge impacts the design of coproduced services and the lives of those with Cystic Fibrosis


Bruce Marshall

M.D., MMM, Chief Medical Officer and Executive Vice President, Cystic Fibrosis (CF) Foundation

Supplementary materials


Trivedi BP. Breath From Salt: A Deadly Genetic Disease, a New Era in Science, and the Patients and Families Who Changed Medicine Forever. 2020 BenBella Books: Dallas, Texas

Karol Fiedorczuk and Jue Chen. “Mechanism of CFTR correction by type I folding correctors.” Cell. Published online January 6, 2022. doi: 10.1016/j.cell.2021.12.009